anastrozole.review http://anastrozole.review anastrozole.review Thu, 05 Oct 2017 19:18:02 +0000 en-US hourly 1 https://wordpress.org/?v=4.4 Anastrozole: the steroid you need http://anastrozole.review/index.php/2016/02/19/anastrozole-the-steroid-you-need/ Fri, 19 Feb 2016 10:01:32 +0000 http://anastrozole.review/?p=35 Release Form Tablets, film-coated. Composition 1 tablet contains: Active ingredients: 1 mg anastrozole. Excipients: lactose monohydrate (200 mesh), lactose monohydrate (spray dried), Povidone K30, sodium carboxymethylstarch (type A), magnesium stearate. The composition of the film-coating: Opadry White 02G28619 (hypromellose (E464), titanium dioxide (E171), macrogol 6000, macrogol 400). Packaging 28 or 56 pieces. pharmachologic effect pharmacodynamics […]

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Release Form

Tablets, film-coated.

Composition

1 tablet contains:

Active ingredients: 1 mg anastrozole.

Excipients: lactose monohydrate (200 mesh), lactose monohydrate (spray dried), Povidone K30, sodium carboxymethylstarch (type A), magnesium stearate.

The composition of the film-coating: Opadry White 02G28619 (hypromellose (E464), titanium dioxide (E171), macrogol 6000, macrogol 400).

Packaging

28 or 56 pieces.

pharmachologic effect

pharmacodynamics

Anticancer agent, an inhibitor of estrogen synthesis.

Anastrozole is highly selective nonsteroidal aromatase inhibitor – an enzyme, whereby in postmenopausal women androstenedione in peripheral tissues is converted into estrone and then to estradiol. Reducing the concentration of circulating estradiol in women with breast cancer has a therapeutic effect. In postmenopausal women, anastrozole at a daily dose of 1 mg estradiol concentration causes a decrease of 80%.

Anastrozole has no progestogenic, androgenic and estrogenic activity. The daily doses of 10 mg to no effect on the secretion of aldosterone and cortisol, therefore the application is not required substitution anastrozole corticosteroids. Details

Pharmacokinetics

Absorption and distribution

 

After oral anastrozole is rapidly absorbed from the gastrointestinal tract. Cmax plasma is usually achieved within 2 hours after ingestion (fasting). Food slightly decreases the rate of absorption, but not its extent and does not result in a clinically significant effect on the Css in plasma drug in single dose daily dose of anastrozole.

 

After 7-day dosing is achieved approximately 90-95% Css anastrozole plasma. Recorded anastrozole pharmacokinetic parameters depending on the time or dose not. Binding to plasma proteins – 40%.

 

Metabolism and excretion

 

Anastrozole is extensively metabolised in postmenopausal women, with less than 10% excreted by the kidneys in unchanged form within 72 hours after ingestion. T1 / 2 of anastrozole plasma is 40-50 hours. Metabolism anastrozole carried N-dealkylation, hydroxylation and glucuronidation. The metabolites of anastrozole are derived primarily by the kidneys. Anastrozole major metabolite – triazol determined in blood plasma does not possess pharmacological activity.

 

Pharmacokinetics in special clinical situations

 

The pharmacokinetics of anastrozole is independent of age in postmenopausal women.

 

Clearance of anastrozole after oral intake in liver cirrhosis or renal dysfunction does not change.

 

testimony

Adjuvant treatment of early breast cancer with positive hormone receptors in postmenopausal women;

first-line treatment of locally advanced breast cancer with positive or unknown hormone receptor in postmenopausal women;

a second line therapy for advanced breast cancer progressing after treatment with tamoxifen.

Contraindications

  • Premenopauznom period;
  • severe hepatic impairment (safety and efficacy have not been established);
  • concomitant therapy with tamoxifen or drugs containing estrogen;
  • pregnancy;
  • lactation (breastfeeding);
  • Children’s age (safety and efficacy in children has not been established);
  • hypersensitivity to anastrozole or other components of the preparation.

Precautions: should be prescribed for osteoporosis, hypercholesterolemia, coronary heart disease, liver dysfunction, severe renal insufficiency (creatinine clearance <20 mL / min), lactase deficiency, lactose intolerance, malabsorption of glucose / galactose (in the dosage form of the drug contains lactose). Read more

 

Dosing and Administration

The drug is taken orally. The tablet is swallowed whole with water. It is recommended to take the drug at the same time, regardless of the meal.

 

Adults, including the elderly, appoint 1 mg orally 1 time / day for a long time. If signs of progression of the disease taking the drug should be discontinued. As an adjuvant therapy recommended duration of treatment – 5 years.

 

If the kidney function dose adjustment is required.

 

Dose adjustment in patients with mild to moderate impaired liver function is not required.

 

Pregnancy and breast-feeding

Contraindicated use of the drug during pregnancy and lactation.

 

Side effects

The frequency of adverse reactions listed below was determined according to the following criteria:

 

  • very often (? 1/10);
  • common (> 1/100, <1/10);
  • sometimes (> 1/1000, <1/100);
  • rare (> 1/10 000, <1/1000);
  • very rare (<1/10 000), including isolated reports.

Since the cardiovascular system: very often – flushing.

 

From the musculoskeletal system: very often – arthralgia; rarely – trigger finger.

 

On the part of the reproductive system: often – dryness of the vaginal mucosa, vaginal bleeding (mainly in the first weeks after the cancellation or replacement of prior hormonal therapy anastrozole).

 

Dermatological reactions: very often – skin rash; often – thinning hair, alopecia; very rarely – erythema multiforme (Stevens-Johnson syndrome).

 

From the digestive system: very often – nausea; often – diarrhea, vomiting, anorexia.

 

On the part of the hepatobiliary system: increased ALT, AST and alkaline phosphatase; rarely – increased activity of GGT and bilirubin, hepatitis.

 

From the nervous system: very often – headache; often – increased drowsiness, carpal tunnel syndrome (mainly observed in patients with risk factors for the disease).

 

On the part of metabolism: often – hypercholesterolemia. The drug can cause a reduction in bone mineral density due to reduced circulating estradiol concentrations, thereby increasing the risk of osteoporosis and bone fractures.

 

Allergic reactions: often – allergic reactions; very rare – anaphylactoid reactions, angioedema, urticaria, anaphylactic shock.

 

Other: very often – asthenia.

 

Drug interactions

Studies on the interaction with the drug cimetidine and antipyrine indicate that clinically significant drug interactions mediated by cytochrome P450 isozymes in the combined use with other drugs anastrozole unlikely. Clinically significant drug interactions when using anastrozole in conjunction with other commonly prescribed drugs available. At the moment, there are no data on the use of anastrozole in combination with other anticancer drugs. Formulations containing estrogen, anastrozole reduced pharmacological action, and therefore, they should not be administered concurrently with anastrozole. There should be appointed along with tamoxifen anastrozole, because it can weaken the pharmacological action of the latter. Details

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Anastrozole: results and side effects for men and women http://anastrozole.review/index.php/2016/02/14/anastrozole-results-and-side-effects-for-men-and-women/ Sun, 14 Feb 2016 05:41:02 +0000 http://anastrozole.review/?p=33 Chemical structure Anastrozole – refers to the anti-androgenic drugs and synthesized specifically dlyalecheniya frequent today among women of the disease – breast cancer. Anastrozole was the first drug that has got into the class of aromatase inhibitors 3rd generation. Anastrozole is capable of reversibly binding aromatase path using competitive inhibition, as well as a preparation […]

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Chemical structure

Anastrozole – refers to the anti-androgenic drugs and synthesized specifically dlyalecheniya frequent today among women of the disease – breast cancer. Anastrozole was the first drug that has got into the class of aromatase inhibitors 3rd generation. Anastrozole is capable of reversibly binding aromatase path using competitive inhibition, as well as a preparation process inhibits the conversion of androgens to estrogens, which are located in peripheral tissues.

The drug has its own chemical name in English – 1,3benzenediatsetonitril, a, a, a ‘, a’-tetramethyl-5- (1 H-1, 2,4triazol-1-ylmethyl), C17H19N5 formula. The molecular weight of 293,366 g / mol. In such applications also often used tamoxifen citrate (Nolvadex), which blocks the effect of estrogen receptors and does not affect the synthesis of endogenous estrogen own body. Details

The drug Anastrozole can have a significant impact on the level of estrogen in the body. For example, the use of 1 mg (usually one tablet) per day can cause a process in which the estrogen is suppressed at 80% or more of patients. Given that has a powerful effect on hormonal drug, it is mainly women prescribed exclusively postmenopausal.

Historical reference

Anastrozole was developed by Zeneca Pharmaceuticals, and the end of 1995 received approval for use in the United States. Medicine was conceived as a new generation tool that will be used for the treatment of more operations to be breast cancers in women. With the same purpose for a long time previously used a drug called Tamoxifen. In order to move from the already well-established trends in this area needed good reasons. Very soon after the emergence of Anastrozole included in a global somatotropin dosage, multicenter, double-blind study destination, which was based in Rome. During the study, evaluated on the use of anastrozole and tamoxifen, alone or combining. In a study of 9366 women took part in postmenopausal after surgery for breast cancer treatment.

According to the results it showed a statistically significant superior efficacy of anastrozole over tamoxifen. After such treatment, a significant number of patients showed regression of the disease, but also increases overall performance for survival.

After the results of the study were published in 2002, the drug Anastrozole received fame as a new tool for the treatment of breast cancer additionality in postmenopausal women. Then he begins to gain popularity among men – athletes, due to the fact that can strongly suppress estrogen. Read more

Mode of action (according to the manufacturer)

Is selective (or selective) non-steroidal aromatase inhibitor nature. During menopause, estradiol largely obtained from estrone, which output occurs in peripheral tissues for the conversion of androstenedione (involving aromatase enzyme). When reducing the volume of circulating estradiol in women with breast cancer therapeutic effect is manifested. During a post-menopausal female body anastrozole in a dosage of 1 mg per day can reduce the level to 80% of estradiol.

The drug Anastrozole is not peculiar progestogenic, androgenic and estrogenic activity. When used at the recommended dose for the treatment of a doctor, the drug has no effect on the process of production of cortisol and aldosterone.

Properties anastrozole

Armideks uniquely interested in athletes who use steroids. Earlier, before it was invented against estrogen fought using Nolvadex and Proviron. When combined course they gave a good effect. In contrast, Arimidex solo has a far greater effect, and therefore become very popular. Use one, and sometimes even ½ tablet gives a stunning result.

When applying silnoaromatiziruyuschihsya drug side effects, such as gynecomastia and water retention, easily blocked. When combined with armideks PROSCAR (finasteride), will minimize the side effects, the occurrence of which involves the use of chords silnoaromatiziruyuschihsya funds and capable of conversion to dihydrotestosterone. Significantly improve the musculature, because excess water will go.

As for sufficiently prolonged administration of any drug, aromatase inhibitors when used may cause problems. Arimidex well able to reduce the side effects of estrogen character, but at the same time, blocking occurs and useful properties of estrogen, such as, the suppression of the “good” cholesterol. If there are problems in the cardio – Nolvadex vascular system, because it carries out the estrogen receptor blockage. Details

The use of anastrozole

  • Reception (for men):

To suppress the effects aromatization athletes sufficiently accept from 500 .mu.g to 1 mg of anastrozole per day.

  • Reception (for women):

Exclusively for medical reasons

Side effects of anastrozole

Mainly to the side effects that arise when taking aromatase inhibitors include hot flashes, joint pain, weakness, fatigue, mood swings, depression, high blood pressure, swelling of hands / feet, as well as headaches. It is also possible decline in bone mineral density, as a result may develop osteoporosis and increased risk of fractures. Sometimes problems can occur in the gastrointestinal tract, as well as nausea and vomiting.

It is strictly forbidden to use during pregnancy, because can disrupt fetal development. When using this type of drugs by men to reduce estrogen for a long time can lead to the development of cardio – vascular diseases due to containment positive impact of estrogen on cholesterol. Studies have found that if we combine steroids having a tendency to aromatization (e.g. testosterone enanthate) together with an aromatase inhibitor begins to show a clear inhibition of HDL (high density lipoproteins, the “good” cholesterol).

Since Tamoxifen basically has such a negative influence on the amount of cholesterol, it is more popular among men – athletes problematic cardio – vascular system than aromatase inhibitors.

Indications for drug use

Breast cancer in postmenopausal women.

Contraindications for medical use

Premenopausal expressed renal insufficiency (creatinine clearance less than 20 ml / min), moderate and clearly marked hepatic impairment, pregnancy and lactation, infancy, hypersensitivity to anastrozole.

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Anastrozole: why bodybuilders need it http://anastrozole.review/index.php/2016/02/09/anastrozole-why-bodybuilders-need-it/ Tue, 09 Feb 2016 08:56:38 +0000 http://anastrozole.review/?p=29 Anastrozole DESCRIPTION BALKAN Anastrozole – a non-steroidal drug, manufactured by Balkan Pharmaceuticals Moldova. Trade name “Anastrozole” is the same and the name of the active substance – Anastrozolum, which is used in this preparation. Anastrozole belongs to a highly selective inhibitors of aromatase (estrogen) of the third generation. The release form – square yellow tablets, […]

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Anastrozole DESCRIPTION BALKAN

Anastrozole – a non-steroidal drug, manufactured by Balkan Pharmaceuticals Moldova. Trade name “Anastrozole” is the same and the name of the active substance – Anastrozolum, which is used in this preparation.

Anastrozole belongs to a highly selective inhibitors of aromatase (estrogen) of the third generation.

The release form – square yellow tablets, the active ingredient in the 1 tab. – 1 mg. Available in blister packs of 20 tablets. The package of 60 tablets, but here you can buy anastrozole in blister. Anastrozole price in pharmacies too high and more expensive times to 10 times than in our online shop.

WHY anastrozole bodybuilding?

Anastrozole does not replace a course of steroids, which are strongly flavored (Drugs with high androgen index.)

As we know excessive aromatization of steroids can cause the development of a variety of estrogen-dependent side effects:

  • development of gynecomastia
  • A set of fat in places that are typical for women (buttocks, hips, breasts)
  • Fluid retention in the body, as a result of the effect of “filled” the muscles, the muscles quickly “hammered” in training.
  • Elevated blood pressure

The use of anastrozole in the AU course avoids the side effects associated with steroid flavoring. Also receiving anastrozole on the course can improve the quality acquired by muscle (the effect of “the muscle stiffness), to increase the amount of free testosterone in the bloodstream of the athlete, leading to more effective drug used. Details

Anastrozole how to make?

Typically, bodybuilders of all kinds are beginning to take anastrozole, only when there are signs of gynecomastia or have gynecomastia appeared (though so we decided to make all preparations to combat gynecomastia).

The best option is renting analysis on estrogen levels, after 10 days, if you are using “short products” – testosterone propionate, methane, or 3-4 weeks if used drugs with a long half-life (testosterone enanthate, cypionate, Sustanon).

If signs of gynecomastia has not yet appeared, half tablets or 0.5 mg. received the next day, would be sufficient to moderate suppression flavoring and prevent side effects. After another 10-14 days, it is desirable to re-pass analysis on estradiol and, if necessary, adjust the dosage up or down. (If you suppress excessive flavoring, taking high dosages, it reduced the effectiveness of the course, and the overall health athlete may decreased libido)

Anastrozole can be administered at any time, regardless of the meal. But the most optimal would be taking the drug for 30 minutes before eating. In this case, the action stuff quickly enters the bloodstream. Read more

As a preventive measure for anastrozole taking 0.5 mg. in one day. Ate at you started the development of gynecomastia, you should take anastrozole 1 mg. everyday. After the disappearance of signs of gynecomastia, you should continue taking prophylactic doses of anastrozole.

Anastrozole in dosages of 1 mg. day courses taken at aromatizing drugs in high dosages.

Buy Anastozol Balkans, you can order in our online store. Anastrozole price in our store is the lowest in Ukraine.

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Anastrozole in bodybuilding and fitness: how to use http://anastrozole.review/index.php/2016/02/03/anastrozole-in-bodybuilding-and-fitness-how-to-use/ Wed, 03 Feb 2016 22:44:20 +0000 http://anastrozole.review/?p=27 The active chemical substance: anastrozole Manufacturer: Balkanfarma Concentration: 1 mg per 1 tablet. The price is for 1 blister (20 tablets) 20 1mg tablets Anastrozole – selective aromatase inhibitor. Anastrozole is used in bodybuilding absolutely at any level, as a freshman, and the hormone-replacement therapy. This preparation is necessary to suppress the flavoring process – […]

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The active chemical substance: anastrozole

Manufacturer: Balkanfarma

Concentration: 1 mg per 1 tablet.

The price is for 1 blister (20 tablets)

20 1mg tablets

Anastrozole – selective aromatase inhibitor. Anastrozole is used in bodybuilding absolutely at any level, as a freshman, and the hormone-replacement therapy. This preparation is necessary to suppress the flavoring process – the conversion of male hormones in the female. When it comes to the point, anastrozole – a drug that was originally used to maintain female hormonal levels. In bodybuilding it found other uses. This is an integral part of any progestagen course, which has the potential to lead to the flavoring. Details

Before starting any course of steroids flavoring always think about where to buy anastrozole. Order drug delivery by mail you can on my site or directly in Minsk. You will be pleasantly surprised anastrozole cost, as well as a selection of his manufacturers. To date, the drug buy on the Internet is easy. In addition, it is not a steroid, so that you have nothing to fear upon delivery.

Here on the site you can get acquainted with photos of anastrozole and with the drug prices. In order to be convinced of the importance of this component of the steroid course, I recommend you read the reviews about the anastrozole, or discuss it on the forum. Thus, you get rid of any doubts regarding its purchase.

The use of anastrozole required for:

  • Reaction flavoring;
  • Suppression of gynecomastia in the early stages;
  • Prevention of fatigue and sleepiness;
  • Controlled set of excess fluid on the course;
  • Fast recovery rate (FCT);
  • Acceleration of muscle recruitment by the normal balance of male and female hormones.

How to receive anastrozole

If you sit on the “compote” drugs, which are easily flavored, then I recommend that you drink 0.5 tablets of anastrozole after 1-2 days. If your arms tests, and you know that aromatization in your body is not very pronounced, the anastrazole on a course at a dosage of one piece every 5-6 days is the most optimal scheme.

For flavoring preparations include: all testosterone esters (propionate, enanthate, cypionate, and others.), Methane (Danabol), methyltestosterone, Equipoise and halotest. Although the latter have a weak estrogenic activity. Read more

When gyno symptoms (itching in the nipples, falling libido, flooded, etc.) to take 1 tablet every day until symptoms disappear. there is an important caveat on the use of anastrozole in the instructions, which only a few know. To wash down pills only need water, they need to be taken on an empty stomach one hour after eating and one hour before the next meal. In this case, the assimilation is complete.

Of course, in addition to anastrozole 1mg rate used during PCT. When you stop to artificially raise the level of testosterone, aromatization remains at a high level. Anastrazolpozvolit suppress the conversion of the remaining testosterone into estrogen, thereby preventing a pronounced pullback phenomenon.

Anastrozole side effects

As with any other drug or drugs in anastrozole are a number of possible side effects. First of all, it is the excessive suppression of flavoring. Male body still need a small amount of female hormones, and anastrozole overdose may lead to their complete absence (zero estradiol levels). For this reason observe appropriate and recommended dosages of anastrozole.

Analogues of anastrozole

Quite often you can hear about the comparisons format: “anastrozole or tamoxifen,” “anastrozole or Proviron,” etc. In practice, such a parallel is not quite correct, since the drugs have different mechanisms of action.

Tamoxifen and Clomid – are drugs that “turn off” receptors that respond to female hormones. The body begins to think that you simply do not have estrogen, while their levels can be quite high. They apply to the PCT after the course so as not to lose muscle mass. During receiving estrogen level falls, but not by receiving Clomid with tamoksom.

Anastrozole does not allow the level of female hormones to climb the highest mark since blocks flavoring. That is why it is used also on the course. This is a completely different mechanism of action.

As for the dispute: “Proviron or anastrozole,” it is all quite simple. Proviron only slightly inhibits aromatase. It is used only for androgenic activity for improving the effectiveness of anabolic courses. With flavoring suppression tasks he can not cope, so it makes anastrozole.

 

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Pharmacology and The mechanism of action of Anastrozole http://anastrozole.review/index.php/2016/01/15/pharmacology-and-the-mechanism-of-action-of-anastrozole/ Fri, 15 Jan 2016 08:23:22 +0000 http://anastrozole.review/?p=16 Pharmacological group: anti-estrogen drugs; non-steroidal aromatase inhibitors. Mode of action: the treatment of advanced breast cancer in women. Systematic (IUPAC) name: 2,2′- [5- (1H-1,2,4-triazol-1-ylmethyl) -1,3-phenylene] bis (2-methylpropanenitrile) Bioavailability: 83-85% Protein binding: 40% Metabolism 85% in the liver The half-life: 46.8 hours Isolation: 11% of renal Formula: C17H19N5 Mol. weight: 293.366 g / mol Anastrozole, available […]

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Pharmacological group: anti-estrogen drugs; non-steroidal aromatase inhibitors.

Mode of action: the treatment of advanced breast cancer in women.

Systematic (IUPAC) name: 2,2′- [5- (1H-1,2,4-triazol-1-ylmethyl) -1,3-phenylene] bis (2-methylpropanenitrile)

Bioavailability: 83-85%

Protein binding: 40%

Metabolism 85% in the liver

The half-life: 46.8 hours

Isolation: 11% of renal

Formula: C17H19N5

Mol. weight: 293.366 g / mol

Anastrozole, available from AstraZeneca under the trade name Arimidex, is a nonsteroidal aromatase inhibitor approved for the treatment of breast cancer after surgery as well as in metastases in women in the pre- and post-menopause. Estrogen increases the severity of breast cancer, as hormones induce hyperplasia and differentiation on the estrogen receptor sites. Anastrozole works by inhibiting estrogen synthesis. The patent for Arimidex by AstraZeneca expired in June 2010.

 

Description

 

Anastrozole – antiestrogen drug developed for the treatment of advanced breast cancer in women. Anastrozole is the first drug in a class of aromatase inhibitors third generation. It acts by inhibiting the enzyme aromatase, and subsequently – by blocking the production of estrogen in the body. Since many forms of breast cancer cells are stimulated by estrogen, reducing levels of the hormone in the body can slow the progression of the disease. For these purposes, it is also often used tamoxifen citrate (Nolvadex), which blocks the action of estrogen receptors, and does not affect the actual endogenous estrogen production by the body. Anastrozole has a significant impact on the level of estrogen in a daily dose of 1 mg (usually one tablet) causes suppression of estrogen more than 80% of patients. Given the powerful effect the drug has on hormone levels, it is usually prescribed only in postmenopausal women. During therapy, may experience side effects such as hot flushes and hair thinning, which are much more likely to occur in premenopausal patients. Read more

 

Anastrozole in bodybuilding

 

Athletes who use steroids, Anastrozole is used in order to minimize the side effects associated with elevated levels of estrogen, is often observed when taking anabolic / androgenic steroids. Compared with traditional drugs such as Nolvadex and Proviron®, Anastrozole can significantly better control of estrogen levels.

 

Tamoxifen Anastrozole against

 

Test ATAC (Arimidex, Tamoxifen, alone or in combination) – an international, randomized, controlled study of 9366 women with localized breast cancer who took either anastrozole or tamoxifen or both drugs at once for five years, followed by five years’ observation. After 5 years of the study, patients of groups whose members received anastrozole, showed significant improvement in clinical outcomes compared to patients in the tamoxifen group. Researchers believe that anastrozole is more preferable as a medical therapy in postmenopausal women with localized estrogen receptor (ER) positive breast cancer. Another study showed that when taking anastrozole risk of relapse was reduced by 40%, but it increases the risk of bone fractures. The study concluded that ER-positive patients who have 2-saving treatment with tamoxifen was beneficial to switch from tamoxifen to anastrozole.

 

The mechanism of action of anastrozole

 

Anastrozole reversibly binds to the aromatase enzyme through competitive inhibition, and inhibits the conversion of androgens to estrogens in peripheral (vnegonadnyh) tissues.

 

History

 

Anastrozole was developed by Zeneca Pharmaceuticals, and in late 1995 was approved for use in the United States. The drug was developed as a new treatment for operable breast cancer in women, which previously, over time, used drug Tamoxifen. To move from the established trends were needed substantial reasons. Shortly after its launch, anastrozole was included in the very large-scale, multicenter, double-blind study, which is based in Rome. The study evaluated the use of anastrozole and tamoxifen, alone or in combination, from 9366 postmenopausal women after breast cancer surgery. The results demonstrate a significant benefit of anastrozole over tamoxifen. As a result, the treatment of patients observed regression of the disease and improve overall survival. After the publication of the study in 2002, anastrozole is becoming known as a new drug for the adjunctive treatment of breast cancer in postmenopausal women. Around the same time, the drug is also becoming popular among men (body builders and athletes), because the drug causes severe suppression of estrogen.

 

How Supplied

 

Anastrozole is often supplied in 1 mg tablets. See more

 

Structural Features

 

Anastrozole is classified as selective non-steroidal aromatase inhibitor. It has the chemical name 1,3benzenediatsetonitril, a, a, a ‘, a’-tetramethyl-5- (1 H-1, 2,4triazol-1-ylmethyl).

 

Anastrozole: side effects

 

Common side effects associated with the use of aromatase inhibitors include: hot flashes, joint pain, weakness, fatigue, mood swings, depression, high blood pressure, swelling of hands / feet, and headache. Aromatase inhibitors can also lead to a decrease in bone mineral density, which can trigger the development of osteoporosis and increase the number of fractures in susceptible patients. Some people may also experience side effects such as problems with the gastrointestinal system, nausea and vomiting. Aromatase inhibitors can harm fetal development, and should not be allowed to use them during pregnancy. When receiving the male (non-label), to reduce levels of estrogens during prolonged periods of steroid therapy, aromatase inhibitors can increase the risk of cardiovascular disease (CVD), holding a positive effect of estrogen on cholesterol levels. Studies have shown that the combination of steroids with a tendency to aromatization, such as testosterone enanthate, inhibitor of aromatase inhibition is more pronounced in high density lipoprotein (HDL, “good” cholesterol). Since an agonist / antagonist estrogen receptor Nolvadex does not usually as antiestrogen (negative) effect on the cholesterol levels, it is usually preferable to bodybuilders and male athletes who have problems with the cardiovascular system than aromatase inhibitors.

 

Anastrozole guide

 

Anastrozole is approved by the FDA as a means for further treatment of postmenopausal women with hormone-positive early breast cancer, as an agent for the treatment of postmenopausal women with hormone-positive or locally advanced metastatic breast cancer, and for the treatment of breast cancer in women in postmenopausal women after tamoxifen therapy. In all cases, the accepted dosage of 1 mg per day to stop disease progression. To mitigate the estrogenic side effects of anabolic / androgenic steroids, male athletes and body builders typically take anastrozole in a dosage of 0.5 mg to 1 mg per day. In some cases, to reduce the accumulation of sufficient estrogen dose is half a tablet (0.5 mg) every other day. When used in combination with an easy flavoring androgens, such as testosterone or methandrostenolone (Dianabol, Methandienone), the drug is able to effectively block gynecomastia and water retention. Furthermore, Anastrozole can be used as a fat burner, since the accumulation of fat is also related to estrogen levels. As a result of taking the drug, the user can expect improved physique that gets more pronounced, the dried kind. The product is of interest to athletes during the diet phase / drying. It should be noted that the absorption anastrozole not affect food intake, and the drug may be taken with meals or between meals.

 

Use of anastrozole for children

 

Anastrozole can be used off-label in children with precocious puberty or in children with pubertal gynecomastia. After the onset of puberty, epiphyseal plate begins to close due to the increased production of estrogen, avoid the local metabolism and spreading through the bloodstream. Anastrozole can help slow down the process and increase the predicted adult height in boys receiving peptide hormones based on proteins for the treatment of growth hormone deficiency.

 

Chemical synthesis of anastrozole

 

The synthesis begins with two nucleophilic substitution of benzylic bromides at a and a ‘dibromomesitilene (obtained by radical bromination mesitylene) by treatment with cyanide, potassium cyanide, under phase transfer conditions to form a dinitrile. Exhaustive methylation with methyl iodide and sodium hydride results in the replacement sidechain more acidic hydrogen atoms by methyl groups. The use of bromine in the presence of benzoyl peroxide results in the formation of the corresponding benzyl bromide. Reaction of this substance 1,2,4-triazole in the presence of a base completes the synthesis of the aromatase inhibitor.

 

Availability:

 

Anastrozole is widely available in the United States and many other countries as a prescription drug. In Russia, the drug is also released from pharmacies by prescription.

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Anastrozole: the use and side effects http://anastrozole.review/index.php/2016/01/15/anastrozole-the-use-and-side-effects/ Fri, 15 Jan 2016 08:21:24 +0000 http://anastrozole.review/?p=14 Anastrozole (Anastrozole) – a powerful non-steroidal drugs used to suppress the phenomenon of depreciation. Anastrozole description. He acts, stopping the depreciation, as well as, ostanvlivaet body’s production of estrogen. Actually, he essentially differs from tamoxifen. It is only estrogen suppresses but does not prevent its occurrence. Anastrozole One dose Anastrozol lowers the amount of estradiol […]

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Anastrozole (Anastrozole) – a powerful non-steroidal drugs used to suppress the phenomenon of depreciation.

Anastrozole description.

He acts, stopping the depreciation, as well as, ostanvlivaet body’s production of estrogen. Actually, he essentially differs from tamoxifen. It is only estrogen suppresses but does not prevent its occurrence.

Anastrozole

One dose Anastrozol lowers the amount of estradiol in the blood within hours.

Those athletes who take a lot of steroids, the drug will be very useful, especially those whose body is prone to flavoring. Earlier, before the drug appeared, in order to prevent flavoring used two drugs: tamoxifen and proveron. Now, this need not. read more

Though when combined, these drugs are highly effective as anastrozole (Anastrozol) is more effective. A dose volume of 1 mg, gives a stunning effect.

During the application of much flavoring agents may be negative consequences, such as fluid retention and gynecomastia. These problems are neutralized without any problems.

And in combination with finasteride, the negative effects of the drugs is converted into Drostanolone actually lower. That’s all give your muscles a high density, as well as to increase them.

There are several important drawbacks discussed preparation:

For all its merits (reduction of estrogenic side effects), it lowers the quality of the positive estrogen, namely, reduces the formation of good cholesterol, which subsequently may cause heart disease. Because people who can threaten it is recommended to take tamoxifen, it only blocks the estrogen receptors, but does not affect the appearance of estradiol. Next negative – financial. The drug has a rather high price.

How to take anastrozole:

Take one tablet daily, or at the beginning of the course, or at the first appearance of symptoms flavoring.

Within 10-12 days, the drug is fully manifest all the properties.

Use only recommended in case of prolonged and challenging courses.

As with any drug, anastrozole has its side effects:

  • – Severe nausea;
  • – diarrhea;
  • – Severe weight loss;
  • – Vomiting;
  • – headache;
  • – An increased desire to sleep;
  • – The appearance of acne;
  • – hair loss;
  • – Allergic reactions.

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Anastrozole or Letrozole: effective post-cycle therapy http://anastrozole.review/index.php/2016/01/15/anastrozole-or-letrozole-effective-post-cycle-therapy/ Fri, 15 Jan 2016 08:20:20 +0000 http://anastrozole.review/?p=12 The content of the article:   Action Anastrozole Application Side effects Anastrozole Women Letrozole in bodybuilding How to take Letrozole Letrozole for women   Among the athletes are very popular drugs such as aromatase inhibitors. These materials can improve anabolic hormones in the blood, to achieve relief, prevent hypertension. Meet with the best representatives of […]

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The content of the article:

 

  • Action Anastrozole
  • Application
  • Side effects
  • Anastrozole Women
  • Letrozole in bodybuilding
  • How to take Letrozole
  • Letrozole for women

 

Among the athletes are very popular drugs such as aromatase inhibitors. These materials can improve anabolic hormones in the blood, to achieve relief, prevent hypertension. Meet with the best representatives of this class.

 

Letrozole and Anastrozole – a better drugs for the treatment of gynecomastia in men, and their use as a prophylactic agent. During the course of anabolic steroids, these drugs are indispensable for bodybuilders. read more

 

Anastrozole in bodybuilding

 

With the assistance of the enzyme aromatase, testosterone is able to turn into the most powerful estrogen – estradiol. The aim of anti-estrogen drugs is to prevent such conversion. These drugs include anastrozole (another name – Arimidex).

 

If you are taking anabolic steroids, this drug will help to minimize the side effects of increased levels of estrogen. This medicine as efficiently controls the level of estrogen.

 

It should highlight the unique properties of anastrozole – for example, the increase in free testosterone. By the way, the drug acts quickly enough. The maximum concentration of active substance in the blood observed after a couple of hours after admission means. This allows you to quickly suppress the flavoring.

 

Action Anastrozole

 

  1. Arimidex is the perfect companion during hormone replacement therapy.

 

  1. The drug holding estrogen at a low level, thereby preventing prostate enlargement.

 

  1. In patients receiving testosterone means can be produced in a natural way, even while taking anabolic-androgen.

 

  1. Anastrozole in bodybuilding – active assistant in the defense of gynecomastia.

 

  1. The drug is mild on blood lipids.

 

  1. Representatives of the stronger sex note that while the use of anastrozole increased libido.

 

  1. This is the most popular drug for post-cycle therapy in the recovery period.

 

Through use of this drug, reduces the accumulation of water and fat during steroid course. It is because of this often misused antiestrogens athletes to compensate for a poor diet or consequences of misuse of anabolic steroids cycle.

 

Excessive reduction in estrogen leads to a decrease in libido. There is depression, slows down muscle growth. Therefore, you should take the drug only in doses which will appoint an expert.

Even in minimal doses of anastrozole is able to control the level of estrogen. This is an effective and safe drug. With regard to high doses, they prescribe a course with vysokoaromatiziruyuschimisya steroids, for example, Danabol. With Anavar or Primobolan quite small doses of the drug. More info

 

Anastrozole: Application

 

Newcomers this tool should not be used. Tablets intended for experienced athletes, after they have been receiving long cycle of anabolic steroids in high doses. Anastrozole is administered on two occasions: before the course of steroids as a prophylactic agent with therapeutic doses, and after a course, if there are side effects.

 

Cycle reception of funds shall not exceed 14 days. During this time, the drug shows its beneficial properties. Take the tablet on an empty stomach and drink plenty of water – so the active ingredient quickly went from the gastrointestinal tract into the bloodstream.

 

This means you need to eat on a strict schedule. One day, taking second – rest. Accepted at any time of the day. Sufficient good results for a dose of 250 micrograms once a couple of days. It is proved that in order to reduce the level of estradiol in the 50% required dosage of 0.5 to 1 milligram.

 

During a cycle necessary to take into account the fact that not all anabolic steroids flavored. At risk are testosterone esters. As for methandrostenolone and Anadrol, they slightly converted into estrogen.

 

If the cycle consists of long esters, for example, Sustanon, you should be tested for estradiol 3-4 weeks after steel to make “chemistry.” In general, it is best to check the test is performed about 10-14 days from the time you started taking anastrozole. So you can adjust the required dose.

 

Those athletes who have started gynecomastia, speak positively about the drug anastrozole. The same applies to letrozole. These drugs effectively relieve the symptoms of breast growth during the course of anabolic steroids.

 

You know, that are prone to this disease? Then always keep handy these medicines. They are affordable. Buy them, you can always in specialized stores. Do not forget that should undergo a mandatory consultation with a medical specialist before starting to cycle.

 

Anastrozole: side effects

 

By the use of anastrozole side effects include:

 

  • drowsiness;
  • erythema multiforme;
  • asthenia;
  • allergic reactions;
  • headache;
  • nausea and vomiting;
  • stomach upset;
  • skin rash.

 

Negative reactions are possible in cases of overdose or if you are hypersensitive to the active substance.

 

Contraindications to receive anastrozole

 

 

If there are problems of the cardiovascular system can not take the medicine. The fact that the means to effectively counteract the side effects of estrogen, but being blocked and its useful properties.

 

As a result, there may be problems with the heart and blood vessels. If athletes have similar diseases, it is imperative to consult a sports doctor, or used tamoxifen.

 

Anastrozole Women

 

The drug has been successfully used in the treatment of breast cancer. Due to the property of lowering the amount of estrogen in the blood, the drug is able to slow the growth of cancer cells and stop the development of this terrible illness. The drug has a powerful hormonal effect, it is only prescribed to women after menopause.

 

For achievements in the sport to take anastrozole for women is strongly discouraged – the female body while taking this medication undesired hormonal changes.

 

Letrozole in bodybuilding

 

Athletes use this drug as an additional element in the course of steroids. With it is possible to reduce the level of estrogen and testosterone increase slightly. The drug can reduce estrogen concentration to nearly 100%, which shows its high efficiency.

 

Through use of letrozole in power sports, increases production of important hormones, which in turn lead to increased production of testosterone.

 

Effect of the drug:

 

  1. Letrozole prevents such side effects like acne and body fat. The same applies to gynecomastia.

 

  1. By taking the drug manages to maintain muscle tissue after cycle reception “chemistry.”

 

  1. It is appropriate to use the medicine when there are aware of anabolic steroids and androgens.

 

How to take Letrozole

 

Cycle receiving fairly long. The drug should be used every day, once a day. Recommended dosage – two and a half milligrams. Large doses can lead to negative consequences, may reduce sexual desire.

 

But in any case, you should consult your doctor – only he, based on the individual characteristics of your body will be able to assign the correct dose and duration of the cycle.

 

Side effects of letrozole:

 

  • headache;
  • pain in the joints;
  • fever;
  • weakness in the body;
  • nausea;
  • hypertension;

 

But all of these side effects may appear only at excessive doses. If you follow the recommendations of the expert, the side effects will not be observed.

 

This tool can use every athlete. Among contra – diseases of the liver and the idiosyncrasy of the components in the composition of letrozole.

 

Letrozole for women

 

The most common cause of death among the fairer sex is a malignant tumor of the breast. This drug helps to cope with this terrible disease in the early stages.

 

The drug is able to inhibit aromatase, which leads to hormonal disorders in the weak half of humanity. As a result, there cancer in postmenopausal women.

 

Due letrozole suppressed estrogen production in tumor tissues. The same applies to peripheral tissues.

 

How to take Letrozole women

 

 

The tablets should be consumed on an empty stomach. The course assigns doctor, dosage, too. The dosage depends on many factors, including the age of the patient. The most common treatment is long – about four or even five years.

 

Tablets are taken once a day. If the disease progresses on a background of the drug, its use is terminated. The tool drawn from the blood almost immediately after administration.

 

Contraindications:

 

 

If a woman has severe liver, during the administration of the drug, it should be under constant medical supervision. The fairer sex who use letrozole should use reliable methods of contraception until a stable post-menopausal hormone status. bodybuilding fitness models rutina de volumen 5 dias best blender for bodybuilders

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Anastrozole in bodybuilding – courses and reviews http://anastrozole.review/index.php/2016/01/15/anastrozole-in-bodybuilding-courses-and-reviews/ Fri, 15 Jan 2016 08:19:43 +0000 http://anastrozole.review/?p=10 The main advantages Rapid suppression of aromatization The powerful inhibitory effect Inhibition of 50% of estrogen Increased levels of testosterone The lack of estrogenic activity Lack progestogenic activity High Absorption Non-steroidal drug Description Anastrozole – tableted preparation of the third generation, a potent inhibitor of aromatase. This highly selective non-steroidal drug is used in the […]

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The main advantages

  • Rapid suppression of aromatization
  • The powerful inhibitory effect
  • Inhibition of 50% of estrogen
  • Increased levels of testosterone
  • The lack of estrogenic activity
  • Lack progestogenic activity
  • High Absorption
  • Non-steroidal drug

Description

Anastrozole – tableted preparation of the third generation, a potent inhibitor of aromatase. This highly selective non-steroidal drug is used in the sport for the prevention of gynecomastia and water retention in the body. Used only when long-term steroid treatment with high doses of drugs. One of the most popular and effective drugs for the prevention of side effects of feminization. It acts much better known Tamoxifen, as it is based on a different principle action.

This drug from the Balkans, you can quickly check the quality. To make sure we sell only first class pharmacological means, visit this page, – www.bp.md, Yupik and use the code.

Quality assurance Anastrozole

Anastrozole: description

This product is intended to inhibit aromatization and reduces its activity by 80-90% of the initial level. From the other drugs it is characterized by high efficiency and speed of action. Already after a couple of hours after the aromatization process is almost entirely blocked by the maximum concentration of the drug.

The operating principle of anastrozole from the Balkans Pharma is fundamentally different from the known Tamoxifen, which blocks estrogen alone, but not to interrupt the process of flavoring. This drug inhibits aromatization itself, hence, estrogens are not synthesized in the body and can not be produced. One-time application in a dose of 1 mg Anastrazole lowers estradiol levels in the blood of 80% in the first hours after administration. Read more

The first products of this type have been developed almost simultaneously with tamoxifen in the 1980s in the United States. Since then, by 1995, there was a third-generation aromatase inhibitors, which concerns this tool and its analogs (Arimidex), and started selling them. In medicine they are used in malignant breast tumors, with high activity of estrogen receptors in the tumor tissue.

Designed to welcome postmenopausal women. Since many breast cancers are stimulated by estrogen, the drug is intended to reduce the amount of estrogen in the blood, thereby slowing the progression of the disease. Some experimental studies of estradiol levels in the blood and decreased to 98% of the initial concentration.

In bodybuilding, the active ingredient of the drug is used to prevent gynecomastia and fluid accumulation, side effects from taking testosterone esters and other drugs with androgenic activity. Recommended only for experienced and professional athletes, conducting courses with esters of testosterone, Sustanon or other medications with androgenic activity.

The cost of Anastrozole (Balkans) is totally justified, since a day is enough with just one pill. Acceptance begin with the start of the course or steroids, or when the first signs of flavoring 0.25 – 1 mg per day. Apply the drug on an empty stomach better because it is faster and more completely absorbed from the gastrointestinal tract into the circulatory system. Maximum concentration in blood reached at 2 hours after administration.

Anastrozole is the right approach for 10-14 days reduces the side effects of severe courses of steroids, in particular flavoring mixes strong drugs. The effectiveness of anti-estrogen and confirmed by numerous clinical trials, but in view of the strength of its impact it is recommended not to all.

Detailed instructions for tablets Anastrozole is available at our Forum where you can get acquainted with individual recommendations for acceptance of the drug. It is advisable to use the drug under the supervision of an experienced specialist. The drug itself has progestogenic and androgenic activity on the secretion of hormones cortisol and aldosterone no effect, it does not require the introduction of corticosteroids during the course.

Anastrozole (anastrozole) has a long half-life (40-50 hours), and, even in small doses, is effective in preventing feminization in athletes. Excreted primarily in the urine and bile. It has no effect on testosterone production. Taking the drug for more than 1 mg per day and for a long time is not recommended.

Reviews of anastrozole

For all the merits of the athletes are two major drawbacks of the drug. Reducing the side effects of estrogen they confirm all reviews Anastrozole (Balkans), so its effectiveness is quite proved. But in the course of action of the active drug and inhibits the synthesis of “good” cholesterol, necessary for the cardiovascular system, it is the first flaw.

Many opinions and our forum is not recommended to use it for people who have problems with the heart or blood vessels. It becomes an alternative to tamoxifen. In combination with finasteride statements are advised to use the drug to minimize pobochek steroids are converted to dihydrotestosterone.

On condition that affects muscles only positive. Having studied the reviews of anastrozole, the second drawback it can be called a relatively high price. Use of the drug is justified in the case of prolonged or courses with high doses of steroids.

Anastrozole: prices

Even the co-administration of Tamoxifen and Proviron does not give the same effect as the drug. Therefore, a sufficiently high price is justified anastrozole efficacy of the drug. People with sensitivity to the drug may be some side effects: acne, nausea, headache, drowsiness, allergic reactions.

The price of high cost due to anastrozole synthesis of the drug, and can often be higher than the price of steroids themselves, which, of course, not happy bodybuilders. But do not skimp on your health. Compare what is more profitable – the price of these tablets or multiple physician visits and conducting surgical operations in the fight against gynecomastia.

The price of this quality product is always higher than cheaper counterparts. So you should keep in mind that if you encounter a shop, where the price of Anastrozole (Balkans) attractively low, make no mistake, this is the first sign of a counterfeit drug. Acquired in our online shops drugs – are the products licensed manufacturing plants sportfarmy. Thus, the authenticity of the purchased means you can check out the UPIK-code on the package, the official website of the manufacturer – www.bp.md

Where to buy Anastrozol

Our online store offers to buy the drug to residents of the Russian Federation and Kazakhstan. Now, even in the most remote regions of these countries to buy the drug anastrozole can be quickly and inexpensively at any time convenient for you. You need only place your order and within a maximum of 15 days of preparation would you.

If you live in Moscow, to buy something Anastrozol be even faster due to fast delivery. Professional athletes just need to take care of their health and to prevent the risk of possible side effects of steroids. Therefore, you need to place your order, the price may be more beneficial to you for large orders. More info

Prevention of gynecomastia and water retention, suppression of estrogen synthesis and flavoring – a good reason to buy Anastrozole (Balkans) in our online store. Payment by electronic money transfer WebMoney, ensuring the reliability and safety of both the seller and the buyer. We guarantee the quality of drugs and numerous feedback from our customers confirm this.

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Anastrozole – comments on the application of the course in bodybuilding http://anastrozole.review/index.php/2016/01/15/anastrozole-comments-on-the-application-of-the-course-in-bodybuilding/ Fri, 15 Jan 2016 08:16:59 +0000 http://anastrozole.review/?p=8 Anastrozole – the new anti-estrogen agent, presented in oral form, based on the active ingredient Anastrozole. On the pharmacological market, it first appeared in 1995. Initially, anastrozole was used only for medical purposes: they conduct therapy of malignant mammary tumors with a high content of estrogen receptors. Now the tool in medicine is not widely […]

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Anastrozole – the new anti-estrogen agent, presented in oral form, based on the active ingredient Anastrozole. On the pharmacological market, it first appeared in 1995. Initially, anastrozole was used only for medical purposes: they conduct therapy of malignant mammary tumors with a high content of estrogen receptors. Now the tool in medicine is not widely applied. In sport it is used mainly by bodybuilders and representatives of the power sports. The main objective of the course anastrozole – avoiding gynecomastia, water retention and other side effects that occur after the end of a long course of treatment with anabolic steroids.

Anastrozole profile

Anastrozole has a very pronounced effect 1 mg of active substance capable of 80% to lower blood levels of estradiol. Even so popular today as the drug Tamoxifen, it does not have such a powerful effect. However, comparing these two tools is not correct, since the principle of their actions are completely different. Read more

The effects from taking Anastrozol

  • How to take Anastrozol significant reduction of flavoring (up to 80% of the initial level).
  • The strong inhibitory effect.
  • Blocking estrogen levels.
  • Rapid effect of the drug. The maximum concentration of active substance in the blood observed after 2 hours after administration, which makes it very quickly suppress the aromatization process.
  • It is very effective for athletes who are prone to flavoring.

How to take Anastrozole

The drug is not recommended for beginners. Tablets Anastrozol used by experienced athletes after a prolonged course of anabolic steroids in high dosages. In sports Anastrzola course can be carried out in two cases: in the event of side effects from steroids (initial signs of flavoring, estrogenic effects) received from 0.25 to 1 milligrams of the drug per day; and applying the drug to the course of steroids as a prophylactic agent with therapeutic dosages. Duration of Anastrozol should not exceed two weeks, this time is enough to make the drug showed their properties. To quickly received the active substance from the gastrointestinal tract into the bloodstream, it is advisable to take it on an empty stomach, washed down with copious amounts of water.

How to take Anastrozole athletes? The drug is contraindicated in women. Those hormonal changes that trigger drug for the female body highly undesirable.

Side effects from Anastrozol

If you are hypersensitive to the active substance, as well as significant excess of recommended dosages, the following side effects of anastrozole: drowsiness, erythema multiforme, fatigue, various allergic reactions, headache, vomiting, nausea, diarrhea, skin rashes. Anastrozol can not apply to people who have problems with the cardiovascular system. The drug is effectively counteracts estrogenic side effects, but at the same time it locks the useful properties of estrogen (suppression of the “good” cholesterol), which can lead to heart problems. Athletes who have CVD, it is necessary to consult with a sports physician or, in extreme cases, to use tamoxifen. More info

Reviews of anastrozole

Reviews Anastrozol examining reviews Anastrozol, it can be concluded that the drug is highly valued as a means of instant antiestrogen effects. This is true, because the maximum concentration of the active ingredient anastrozole observed in the first few hours after his admission.

The most commendable reviews of Anastrozole tablets can be heard among professional athletes in bodybuilding. Experienced athletes are satisfied with the quality of the lock after long exposure to estrogen and powerful course AAS.

Preparations based on anastrozole

Manufacturer Name
Alpha Pharma Anazole
Balkan Pharmaceuticals Anastrozol
G-Tech Pharmaceuticals Anastrotabs
Pharmacom Labs Anastrazolos
Radjay Pharmaceuticals Anastrozole
Vermodje Anastrover
Zhengzhou Pharmaceutical Anastrozole

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A brief description of Anastrozole http://anastrozole.review/index.php/2016/01/15/a-brief-description-of-anastrozole/ Fri, 15 Jan 2016 08:15:23 +0000 http://anastrozole.review/?p=6 Anti estrogen drugs of the new generation. The main component – the active ingredient Anastrozole. For the first time the drug appeared on the market in 1995. First means are used exclusively for medical purposes. Anastrozole is used in the treatment of various tumors. Today in medicine drug is not widely applied. Basically anastrozololom are […]

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Anti estrogen drugs of the new generation. The main component – the active ingredient Anastrozole.

For the first time the drug appeared on the market in 1995. First means are used exclusively for medical purposes. Anastrozole is used in the treatment of various tumors. Today in medicine drug is not widely applied. Basically anastrozololom are bodybuilders. Action medicines:

  1. It avoids gynecomastia
  2. Eliminates fluid retention, edema
  3. It eliminates the effects of receiving very potent steroids

Just 1 mg 80% reduction in blood estradiol. It is also observed:

  • Blocking estrogen levels
  • Reduced flavoring
  • The powerful inhibitory effect

After about two hours there is the maximum concentration of Anastrozole. Therefore, the substance is incredibly fast helps athletes who are prone to the emergence of flavoring. More information here

Admission Regulations

We do not advise beginners to take anastrozole. The tool is applied only after prolonged steroid course in high dosages. The tablets are: ·

  • If there are side effects of steroids
  • For prevention

When signs flavoring agent is the daily dose of 0.25-1 mg. To activate the effect of the drug taking pills on an empty stomach. Do not forget to drink the medicine with water. With such a reception Anastrozole quickly enters the bloodstream from the gastrointestinal tract. Remember – the duration of the use of anastrozole in any case should not exceed 2 weeks. Do not take the drug to women. Anastrozole contributes to the rapid hormonal changes, which is highly undesirable for the body athletes.

Side effects

If you exceed the allowable dose, and are hypersensitive to possible occurrence:

  • Asthenia
  • Erythema multiforme
  • Nausea
  • Sleepiness
  • Allergic reactions
  • Diarrhea
  • Headaches
  • Skin rashes

Anastrozole is contraindicated if you have a disease of the cardiovascular system. The tool suppresses the production of good cholesterol. Athletes with CVD before taking the drug should consult a doctor.

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